Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression

Individuals carrying mutations in BRCA1 or p53 genes are predisposed to a variety of cancers, and both tumor suppressor genes have been implicated in DNA damage response pathways. We have analyzed a possible functional link between p53 and BRCA1 genes. Here we show that BRCA1 expression levels are d...

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Autors principals: Arizti, Paz, Fang, Li, Park, Iha, Yin, Yuxin, Solomon, Ellen, Ouchi, Toru, Aaronson, Stuart A., Lee, Sam W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86298/
https://ncbi.nlm.nih.gov/pubmed/11003642
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