Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells.

Growth factor stimulation of the mitogen-activated protein (MAP) kinase pathway in fibroblasts is inhibited by cyclic AMP (cAMP) as a result of inhibition of Raf-1. In contrast, cAMP inhibits neither nerve growth factor-induced MAP kinase activation nor differentiation in PC12 pheochromocytoma cells...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Erhardt, P, Troppmair, J, Rapp, U R, Cooper, G M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.10.5524
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