Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression

Individuals carrying mutations in BRCA1 or p53 genes are predisposed to a variety of cancers, and both tumor suppressor genes have been implicated in DNA damage response pathways. We have analyzed a possible functional link between p53 and BRCA1 genes. Here we show that BRCA1 expression levels are d...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Arizti, Paz, Fang, Li, Park, Iha, Yin, Yuxin, Solomon, Ellen, Ouchi, Toru, Aaronson, Stuart A., Lee, Sam W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7450-7459.2000
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