Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction.

We have investigated the relationship between hydrolysis of phosphatidylcholine (PC) and activation of the Raf-1 protein kinase in Ras-mediated transduction of mitogenic signals. As previously reported, cotransfection of a PC-specific phospholipase C (PC-PLC) expression plasmid bypassed the block to...

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Detalhes bibliográficos
Main Authors: Cai, H, Erhardt, P, Troppmair, J, Diaz-Meco, M T, Sithanandam, G, Rapp, U R, Moscat, J, Cooper, G M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC364836/
https://ncbi.nlm.nih.gov/pubmed/8246981
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