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Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction.

We have investigated the relationship between hydrolysis of phosphatidylcholine (PC) and activation of the Raf-1 protein kinase in Ras-mediated transduction of mitogenic signals. As previously reported, cotransfection of a PC-specific phospholipase C (PC-PLC) expression plasmid bypassed the block to...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Cai, H, Erhardt, P, Troppmair, J, Diaz-Meco, M T, Sithanandam, G, Rapp, U R, Moscat, J, Cooper, G M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 1993
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364836/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7645-7651.1993
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