Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells.

We used a dominant inhibitory mutation of c-Ha-ras which changes Ser-17 to Asn-17 in the gene product p21 [p21(Asn-17)Ha-ras] to investigate ras function in mitogenic signal transduction. An NIH 3T3 cell line [NIH(M17)] was isolated that displayed inducible expression of the mutant Ha-ras gene (Ha-r...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Cai, H, Szeberényi, J, Cooper, G M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.10.5314-5323.1990
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