Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction.

We have investigated the relationship between hydrolysis of phosphatidylcholine (PC) and activation of the Raf-1 protein kinase in Ras-mediated transduction of mitogenic signals. As previously reported, cotransfection of a PC-specific phospholipase C (PC-PLC) expression plasmid bypassed the block to...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Cai, H, Erhardt, P, Troppmair, J, Diaz-Meco, M T, Sithanandam, G, Rapp, U R, Moscat, J, Cooper, G M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7645-7651.1993
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