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p53 Regulation of G(2) Checkpoint Is Retinoblastoma Protein Dependent

In the present study, we investigated the role of p53 in G(2) checkpoint function by determining the mechanism by which p53 prevents premature exit from G(2) arrest after genotoxic stress. Using three cell model systems, each isogenic, we showed that either ectopic or endogenous p53 sustained a G(2)...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphov: Flatt, Patricia M., Tang, Luo Jia, Scatena, Caroline D., Szak, Suzanne T., Pietenpol, Jennifer A.
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85790/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4210-4223.2000
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