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Differential Transactivation by the p53 Transcription Factor Is Highly Dependent on p53 Level and Promoter Target Sequence

Little is known about the mechanisms that regulate differential transactivation by p53. We developed a system in the yeast Saccharomyces cerevisiae that addresses p53 transactivation capacity from 26 different p53 response elements (REs) under conditions where all other factors, such as chromatin, a...

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Detalhes bibliográficos
Main Authors: Inga, Alberto, Storici, Francesca, Darden, Thomas A., Resnick, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139870/
https://ncbi.nlm.nih.gov/pubmed/12446780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8612-8625.2002
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