p53 Regulation of G(2) Checkpoint Is Retinoblastoma Protein Dependent

In the present study, we investigated the role of p53 in G(2) checkpoint function by determining the mechanism by which p53 prevents premature exit from G(2) arrest after genotoxic stress. Using three cell model systems, each isogenic, we showed that either ectopic or endogenous p53 sustained a G(2)...

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Detaylı Bibliyografya
Asıl Yazarlar: Flatt, Patricia M., Tang, Luo Jia, Scatena, Caroline D., Szak, Suzanne T., Pietenpol, Jennifer A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Cell Growth and Development
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC85790/
https://ncbi.nlm.nih.gov/pubmed/10825186
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