p53 Regulation of G(2) Checkpoint Is Retinoblastoma Protein Dependent

In the present study, we investigated the role of p53 in G(2) checkpoint function by determining the mechanism by which p53 prevents premature exit from G(2) arrest after genotoxic stress. Using three cell model systems, each isogenic, we showed that either ectopic or endogenous p53 sustained a G(2)...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Flatt, Patricia M., Tang, Luo Jia, Scatena, Caroline D., Szak, Suzanne T., Pietenpol, Jennifer A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825186/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4210-4223.2000
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