Cellular Response to Oncogenic Ras Involves Induction of the Cdk4 and Cdk6 Inhibitor p15(INK4b)

The cell cycle inhibitor p15(INK4b) is frequently inactivated by homozygous deletion together with p16(INK4a) and p19(ARF) in some types of tumors. Although the tumor suppressor capability of p15(INK4b) is still questioned, it has been found to be specifically inactivated by hypermethylation in hema...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Malumbres, Marcos, Pérez De Castro, Ignacio, Hernández, María I., Jiménez, María, Corral, Teresa, Pellicer, Angel
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2000
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85529/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10733595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.8.2915-2925.2000
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