טוען...
Haploinsufficiency of p18(INK4c) Sensitizes Mice to Carcinogen-Induced Tumorigenesis
The INK4 family of cyclin-dependent kinase (CDK) inhibitors negatively regulates cyclin D-dependent CDK4 and CDK6 and thereby retains the growth-suppressive function of Rb family proteins. Mutations in the CDK4 gene conferring INK4 resistance are associated with familial and sporadic melanoma in hum...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2003
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141153/ https://ncbi.nlm.nih.gov/pubmed/12556487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1269-1277.2003 |
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