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Biochemical and Genetic Interactions between Drosophila Caspases and the Proapoptotic Genes rpr, hid, and grim

In Drosophila melanogaster, the induction of apoptosis requires three closely linked genes, reaper (rpr), head involution defective (hid), and grim. The products of these genes induce apoptosis by activating a caspase pathway. Two very similar Drosophila caspases, DCP-1 and drICE, have been previous...

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Bibliografiske detaljer
Main Authors: Song, Zhiwei, Guan, Bo, Bergman, Andreas, Nicholson, Donald W., Thornberry, Nancy A., Peterson, Erin P., Steller, Hermann
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85526/
https://ncbi.nlm.nih.gov/pubmed/10733594
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