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The proapoptotic function of Drosophila Hid is conserved in mammalian cells

Three genes—reaper, grim, and hid—are crucial to the regulation of programmed cell death in Drosophila melanogaster. Mutations involving all three genes virtually abolish apoptosis during development, and homozygous hid mutants die as embryos with extensive defects in apoptosis. Although Hid is cent...

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Détails bibliographiques
Auteurs principaux: Haining, W. N., Carboy-Newcomb, C., Wei, C. L., Steller, H.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC21795/
https://ncbi.nlm.nih.gov/pubmed/10220397
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