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The proapoptotic function of Drosophila Hid is conserved in mammalian cells

Three genes—reaper, grim, and hid—are crucial to the regulation of programmed cell death in Drosophila melanogaster. Mutations involving all three genes virtually abolish apoptosis during development, and homozygous hid mutants die as embryos with extensive defects in apoptosis. Although Hid is cent...

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Hlavní autoři: Haining, W. N., Carboy-Newcomb, C., Wei, C. L., Steller, H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC21795/
https://ncbi.nlm.nih.gov/pubmed/10220397
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