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CDK7 Regulates the Mitochondrial Localization of a Tail-Anchored Proapoptotic Protein, Hid

The mitochondrial outer membrane is a major site of apoptosis regulation across phyla. Human and C. elegans Bcl-2 family proteins and Drosophila Hid require the C-terminal tail-anchored (TA) sequence in order to insert into the mitochondrial membrane, but it remains unclear whether cytosolic protein...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Jun Morishita, Min-Ji Kang, Kevin Fidelin, Hyung Don Ryoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2013-12-01
Schriftenreihe:Cell Reports
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2211124713006979
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