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Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

Induction of apoptosis in Drosophila requires the activity of three closely linked genes, reaper, hid and grim. Here we show that the proteins encoded by reaper, hid and grim activate cell death by inhibiting the anti-apoptotic activity of the Drosophila IAP1 (diap1) protein. In a genetic modifier s...

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Bibliografski detalji
Glavni autori: Goyal, Lakshmi, McCall, Kimberly, Agapite, Julie, Hartwieg, Erika, Steller, Hermann
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305597/
https://ncbi.nlm.nih.gov/pubmed/10675328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.589
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