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Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
Induction of apoptosis in Drosophila requires the activity of three closely linked genes, reaper, hid and grim. Here we show that the proteins encoded by reaper, hid and grim activate cell death by inhibiting the anti-apoptotic activity of the Drosophila IAP1 (diap1) protein. In a genetic modifier s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305597/ https://ncbi.nlm.nih.gov/pubmed/10675328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.589 |
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