Molecular Mechanism for the Shp-2 Tyrosine Phosphatase Function in Promoting Growth Factor Stimulation of Erk Activity

We have previously shown that activation of extracellular signal-regulated kinase (Erk) by epidermal growth factor (EGF) treatment was significantly decreased in mouse fibroblast cells expressing a mutant Shp-2 molecule lacking 65 amino acids in the SH2-N domain, Shp-2(Δ46-110). To address the molec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shi, Zhong-Qing, Yu, De-Hua, Park, Morag, Marshall, Mark, Feng, Gen-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85329/
https://ncbi.nlm.nih.gov/pubmed/10669730
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados