The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Epithelial morphogenesis is critical during development and wound healing, and alterations in this program contribute to neoplasia. Met, the hepatocyte growth factor (HGF) receptor, promotes a morphogenic program in epithelial cell lines in matrix cultures. Previous studies have identified Gab1, the...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Maroun, Christiane R., Naujokas, Monica A., Holgado-Madruga, Marina, Wong, Albert J., Park, Morag
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11046147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.22.8513-8525.2000
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