The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Epithelial morphogenesis is critical during development and wound healing, and alterations in this program contribute to neoplasia. Met, the hepatocyte growth factor (HGF) receptor, promotes a morphogenic program in epithelial cell lines in matrix cultures. Previous studies have identified Gab1, the...

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Bibliografiska uppgifter
Huvudupphovsmän: Maroun, Christiane R., Naujokas, Monica A., Holgado-Madruga, Marina, Wong, Albert J., Park, Morag
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Cell Growth and Development
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC102157/
https://ncbi.nlm.nih.gov/pubmed/11046147
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