Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2

The nontransmembrane protein tyrosine phosphatase SHP-2 plays a critical role in growth factor and cytokine signaling pathways. Previous studies revealed that a fraction of SHP-2 moves to focal contacts upon integrin engagement and that SHP-2 binds to SHP substrate 1 (SHPS-1)/SIRP-1α, a transmembran...

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Detalhes bibliográficos
Main Authors: Oh, Eok-Soo, Gu, Haihua, Saxton, Tracy M., Timms, John F., Hausdorff, Sharon, Frevert, Ernst U., Kahn, Barbara B., Pawson, Tony, Neel, Benjamin G., Thomas, Sheila M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84114/
https://ncbi.nlm.nih.gov/pubmed/10082587
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