Receptor-Specific Regulation of Phosphatidylinositol 3′-Kinase Activation by the Protein Tyrosine Phosphatase Shp2

Receptor tyrosine kinases (RTKs) play distinct roles in multiple biological systems. Many RTKs transmit similar signals, raising questions about how specificity is achieved. One potential mechanism for RTK specificity is control of the magnitude and kinetics of activation of downstream pathways. We...

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Detalles Bibliográficos
Main Authors: Zhang, Si Qing, Tsiaras, William G., Araki, Toshiyuki, Wen, Gengyun, Minichiello, Liliana, Klein, Ruediger, Neel, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133866/
https://ncbi.nlm.nih.gov/pubmed/12024020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4062-4072.2002
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