Normal Hematopoiesis and Inflammatory Responses Despite Discrete Signaling Defects in Gα15 Knockout Mice

Gα15 activates phospholipase Cβ in response to the greatest variety of agonist-stimulated heptahelical receptors among the four Gq class G-protein α subunits expressed in mammals. Gα15 is primarily expressed in hematopoietic cells in fetal and adult mice. We disrupted the Gα15 gene by homologous rec...

Descrición completa

Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Davignon, I., Catalina, M. D., Smith, D., Montgomery, J., Swantek, J., Croy, J., Siegelman, M., Wilkie, T. M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2000
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10629036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.3.797-804.2000
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!