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Hemorrhage, Impaired Hematopoiesis, and Lethality in Mouse Embryos Carrying a Targeted Disruption of the Fli1 Transcription Factor

The Ets family of transcription factors have been suggested to function as key regulators of hematopoeisis. Here we describe aberrant hematopoeisis and hemorrhaging in mouse embryos homozygous for a targeted disruption in the Ets family member, Fli1. Mutant embryos are found to hemorrhage from the d...

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Autors principals: Spyropoulos, Demetri D., Pharr, Pamela N., Lavenburg, Kim R., Jackers, Pascale, Papas, Takis S., Ogawa, Makio, Watson, Dennis K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86032/
https://ncbi.nlm.nih.gov/pubmed/10891501
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