Hemorrhage, Impaired Hematopoiesis, and Lethality in Mouse Embryos Carrying a Targeted Disruption of the Fli1 Transcription Factor

The Ets family of transcription factors have been suggested to function as key regulators of hematopoeisis. Here we describe aberrant hematopoeisis and hemorrhaging in mouse embryos homozygous for a targeted disruption in the Ets family member, Fli1. Mutant embryos are found to hemorrhage from the d...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Spyropoulos, Demetri D., Pharr, Pamela N., Lavenburg, Kim R., Jackers, Pascale, Papas, Takis S., Ogawa, Makio, Watson, Dennis K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5643-5652.2000
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