Hemorrhage, Impaired Hematopoiesis, and Lethality in Mouse Embryos Carrying a Targeted Disruption of the Fli1 Transcription Factor

The Ets family of transcription factors have been suggested to function as key regulators of hematopoeisis. Here we describe aberrant hematopoeisis and hemorrhaging in mouse embryos homozygous for a targeted disruption in the Ets family member, Fli1. Mutant embryos are found to hemorrhage from the d...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Spyropoulos, Demetri D., Pharr, Pamela N., Lavenburg, Kim R., Jackers, Pascale, Papas, Takis S., Ogawa, Makio, Watson, Dennis K.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 2000
נושאים:	Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5643-5652.2000
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