Hemorrhage, Impaired Hematopoiesis, and Lethality in Mouse Embryos Carrying a Targeted Disruption of the Fli1 Transcription Factor

The Ets family of transcription factors have been suggested to function as key regulators of hematopoeisis. Here we describe aberrant hematopoeisis and hemorrhaging in mouse embryos homozygous for a targeted disruption in the Ets family member, Fli1. Mutant embryos are found to hemorrhage from the d...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Spyropoulos, Demetri D., Pharr, Pamela N., Lavenburg, Kim R., Jackers, Pascale, Papas, Takis S., Ogawa, Makio, Watson, Dennis K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5643-5652.2000
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