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G Alpha-q/11 Protein Plays a Key Role in Insulin-Induced Glucose Transport in 3T3-L1 Adipocytes

We evaluated the role of the G alpha-q (Gαq) subunit of heterotrimeric G proteins in the insulin signaling pathway leading to GLUT4 translocation. We inhibited endogenous Gαq function by single cell microinjection of anti-Gαq/11 antibody or RGS2 protein (a GAP protein for Gαq), followed by immunosta...

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Detalhes bibliográficos
Main Authors: Imamura, Takeshi, Vollenweider, Peter, Egawa, Katsuya, Clodi, Martin, Ishibashi, Kenichi, Nakashima, Naoki, Ugi, Satoshi, Adams, John W., Brown, Joan Heller, Olefsky, Jerrold M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84673/
https://ncbi.nlm.nih.gov/pubmed/10490615
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