G Alpha-q/11 Protein Plays a Key Role in Insulin-Induced Glucose Transport in 3T3-L1 Adipocytes

We evaluated the role of the G alpha-q (Gαq) subunit of heterotrimeric G proteins in the insulin signaling pathway leading to GLUT4 translocation. We inhibited endogenous Gαq function by single cell microinjection of anti-Gαq/11 antibody or RGS2 protein (a GAP protein for Gαq), followed by immunosta...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Imamura, Takeshi, Vollenweider, Peter, Egawa, Katsuya, Clodi, Martin, Ishibashi, Kenichi, Nakashima, Naoki, Ugi, Satoshi, Adams, John W., Brown, Joan Heller, Olefsky, Jerrold M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84673/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.6765
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