Insulin Induces Heterologous Desensitization of G Protein-Coupled Receptor and Insulin-Like Growth Factor I Signaling by Downregulating β-Arrestin-1

β-Arrestin-1 mediates agonist-dependent desensitization and internalization of G protein-coupled receptors (GPCRs) and is also essential for GPCR mitogenic signaling. In addition, insulin-like growth factor I receptor (IGF-IR) endocytosis is facilitated by β-arrestin-1, and internalization is necess...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dalle, Stéphane, Imamura, Takeshi, Rose, David W., Sears Worrall, Dorothy, Ugi, Satoshi, Hupfeld, Christopher J., Olefsky, Jerrold M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6272-6285.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!