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Transcription Factor E2F-1 Is Upregulated in Response to DNA Damage in a Manner Analogous to That of p53

The transcription factor E2F-1 directs the expression of genes that induce or regulate cell division, and a role for E2F-1 in driving cells into apoptosis is the subject of intense discussion. Recently it has been shown that E2F-1 binds and coprecipitates with the mouse double-minute chromosome 2 pr...

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Bibliographic Details
Main Authors: Blattner, Christine, Sparks, Alison, Lane, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84185/
https://ncbi.nlm.nih.gov/pubmed/10207094
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