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Involvement of the DNA Repair Protein hHR23 in p53 Degradation
The stability of the tumor suppressor protein p53 is regulated via the ubiquitin-proteasome-dependent proteolytic pathway. Like most substrates of this pathway, p53 is modified by the attachment of polyubiquitin chains prior to proteasome-mediated degradation. However, the mechanism(s) involved in t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309646/ https://ncbi.nlm.nih.gov/pubmed/14645509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.24.8960-8969.2003 |
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