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Involvement of the DNA Repair Protein hHR23 in p53 Degradation

The stability of the tumor suppressor protein p53 is regulated via the ubiquitin-proteasome-dependent proteolytic pathway. Like most substrates of this pathway, p53 is modified by the attachment of polyubiquitin chains prior to proteasome-mediated degradation. However, the mechanism(s) involved in t...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Glockzin, Sandra, Ogi, Francois-Xavier, Hengstermann, Arnd, Scheffner, Martin, Blattner, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.24.8960-8969.2003
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