p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

The p53 tumor suppressor protein is a sequence-specific transcription factor that modulates the response of cells to DNA damage. Recent studies suggest that full transcriptional activity of p53 requires the coactivators CREB binding protein (CBP)/p300 and PCAF. These coactivators interact with each...

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Autores principales: Liu, Lin, Scolnick, Daniel M., Trievel, Raymond C., Zhang, Hong Bing, Marmorstein, Ronen, Halazonetis, Thanos D., Berger, Shelley L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC116049/
https://ncbi.nlm.nih.gov/pubmed/9891054
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