Role for Caspase-Mediated Cleavage of Rad51 in Induction of Apoptosis by DNA Damage

We report here that the Rad51 recombinase is cleaved in mammalian cells during the induction of apoptosis by ionizing radiation (IR) exposure. The results demonstrate that IR induces Rad51 cleavage by a caspase-dependent mechanism. Further support for involvement of caspases is provided by the findi...

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Xehetasun bibliografikoak

Argitaratua izan da:	Mol Cell Biol
Egile Nagusiak:	Huang, YinYin, Nakada, Shuji, Ishiko, Takatoshi, Utsugisawa, Taiju, Datta, Rakesh, Kharbanda, Surender, Yoshida, Kiyotsugu, Talanian, Robert V., Weichselbaum, Ralph, Kufe, Donald, Yuan, Zhi-Min
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis 1999
Gaiak:	Cell Growth and Development
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2986
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