Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage

The c-Abl protein tyrosine kinase is activated by certain DNA-damaging agents and regulates induction of the stress-activated c-Jun N-terminal protein kinase (SAPK). Here we show that nuclear c-Abl associates with MEK kinase 1 (MEKK-1), an upstream effector of the SEK1→SAPK pathway, in the response...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kharbanda, Surender, Pandey, Pramod, Yamauchi, Teruo, Kumar, Shailender, Kaneki, Masao, Kumar, Vijay, Bharti, Ajit, Yuan, Zhi-Min, Ghanem, Louis, Rana, Ajay, Weichselbaum, Ralph, Johnson, Gary, Kufe, Donald
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10866655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.14.4979-4989.2000
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