Targeting of the c-Abl Tyrosine Kinase to Mitochondria in Endoplasmic Reticulum Stress-Induced Apoptosis

The ubiquitously expressed c-Abl tyrosine kinase localizes to the nucleus and cytoplasm. Using confocal microscopy, we demonstrated that c-Abl colocalizes with the endoplasmic reticulum (ER)-associated protein grp78. Expression of c-Abl in the ER was confirmed by immunoelectron microscopy. Subcellul...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ito, Yasumasa, Pandey, Pramod, Mishra, Neerad, Kumar, Shailendra, Narula, Navneet, Kharbanda, Surender, Saxena, Satya, Kufe, Donald
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11509666/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.18.6233-6242.2001
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