Role for Caspase-Mediated Cleavage of Rad51 in Induction of Apoptosis by DNA Damage

We report here that the Rad51 recombinase is cleaved in mammalian cells during the induction of apoptosis by ionizing radiation (IR) exposure. The results demonstrate that IR induces Rad51 cleavage by a caspase-dependent mechanism. Further support for involvement of caspases is provided by the findi...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Huang, YinYin, Nakada, Shuji, Ishiko, Takatoshi, Utsugisawa, Taiju, Datta, Rakesh, Kharbanda, Surender, Yoshida, Kiyotsugu, Talanian, Robert V., Weichselbaum, Ralph, Kufe, Donald, Yuan, Zhi-Min
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 1999
Aiheet:	Cell Growth and Development
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2986
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!