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Protein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72

Various stresses activate the c-Jun N-terminal kinase (JNK), which is involved in the regulation of many aspects of cellular physiology, including apoptosis. Here we demonstrate that in contrast to UV irradiation, heat shock causes little or no stimulation of the JNK-activating kinase SEK1, while kn...

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Udgivet i:Mol Cell Biol
Principais autores: Meriin, Anatoli B., Yaglom, Julia A., Gabai, Vladimir L., Mosser, Dick D., Zon, Leonard, Sherman, Michael Y.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84047/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2547
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