Protein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72

Various stresses activate the c-Jun N-terminal kinase (JNK), which is involved in the regulation of many aspects of cellular physiology, including apoptosis. Here we demonstrate that in contrast to UV irradiation, heat shock causes little or no stimulation of the JNK-activating kinase SEK1, while kn...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Meriin, Anatoli B., Yaglom, Julia A., Gabai, Vladimir L., Mosser, Dick D., Zon, Leonard, Sherman, Michael Y.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2547
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