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Human Topoisomerase I Promotes Initiation of Simian Virus 40 DNA Replication In Vitro

Addition of purified human topoisomerase I (topo I) to simian virus 40 T antigen-driven in vitro DNA replication reactions performed with topo I-deficient extracts results in a greater than 10-fold stimulation of completed molecules as well as a more than 3-fold enhancement of overall DNA replicatio...

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Udgivet i:Mol Cell Biol
Principais autores: Trowbridge, Pamela W., Roy, Rupa, Simmons, Daniel T.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10022856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.3.1686
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