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Human Topoisomerase I Promotes Initiation of Simian Virus 40 DNA Replication In Vitro

Addition of purified human topoisomerase I (topo I) to simian virus 40 T antigen-driven in vitro DNA replication reactions performed with topo I-deficient extracts results in a greater than 10-fold stimulation of completed molecules as well as a more than 3-fold enhancement of overall DNA replicatio...

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Detalhes bibliográficos
Principais autores: Trowbridge, Pamela W., Roy, Rupa, Simmons, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC83962/
https://ncbi.nlm.nih.gov/pubmed/10022856
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