Activated MEK Stimulates Expression of AP-1 Components Independently of Phosphatidylinositol 3-Kinase (PI3-Kinase) but Requires a PI3-Kinase Signal To Stimulate DNA Synthesis

To investigate the contribution that ERK/mitogen-activated protein kinase signalling makes to cell cycle progression and gene expression, we have constructed cell lines to express an inducible version of activated MEK1. Using these cells, we show that activation of MEK leads to the expression of Fra...

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Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Treinies, Iris, Paterson, Hugh F., Hooper, Steven, Wilson, Rebecca, Marshall, Christopher J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1999
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.321
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