MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.

MEK-1 is a dual threonine and tyrosine recognition kinase that phosphorylates and activates mitogen-activated protein kinase (MAPK). MEK-1 is in turn activated by phosphorylation. Raf and MAPK/extracellular signal-regulated kinase kinase (MEKK) independently phosphorylate and activate MEK-1. Recombi...

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Publié dans:	Mol Biol Cell
Auteurs principaux:	Gardner, A M, Vaillancourt, R R, Lange-Carter, C A, Johnson, G L
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Cell Biology 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8019005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.2.193
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