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MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.

MEK-1 is a dual threonine and tyrosine recognition kinase that phosphorylates and activates mitogen-activated protein kinase (MAPK). MEK-1 is in turn activated by phosphorylation. Raf and MAPK/extracellular signal-regulated kinase kinase (MEKK) independently phosphorylate and activate MEK-1. Recombi...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Principais autores: Gardner, A M, Vaillancourt, R R, Lange-Carter, C A, Johnson, G L
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Cell Biology 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8019005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.2.193
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