MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.

MEK-1 is a dual threonine and tyrosine recognition kinase that phosphorylates and activates mitogen-activated protein kinase (MAPK). MEK-1 is in turn activated by phosphorylation. Raf and MAPK/extracellular signal-regulated kinase kinase (MEKK) independently phosphorylate and activate MEK-1. Recombi...

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Main Authors: Gardner, A M, Vaillancourt, R R, Lange-Carter, C A, Johnson, G L
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC301025/
https://ncbi.nlm.nih.gov/pubmed/8019005
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