Activated MEK Stimulates Expression of AP-1 Components Independently of Phosphatidylinositol 3-Kinase (PI3-Kinase) but Requires a PI3-Kinase Signal To Stimulate DNA Synthesis

To investigate the contribution that ERK/mitogen-activated protein kinase signalling makes to cell cycle progression and gene expression, we have constructed cell lines to express an inducible version of activated MEK1. Using these cells, we show that activation of MEK leads to the expression of Fra...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Treinies, Iris, Paterson, Hugh F., Hooper, Steven, Wilson, Rebecca, Marshall, Christopher J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.321
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