Elevated serum gasdermin D N-terminal implicates monocyte and macrophage pyroptosis in adult-onset Still's disease

OBJECTIVES: Elevation of serum IL-18 in adult-onset Still's disease (AOSD) and systemic JIA (sJIA) suggests the role of the inflammasome in these diseases. Gasdermin D is a pore-forming protein playing central roles in inflammasome-mediated inflammation, but its role in rheumatic disease is unk...

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Sparad:
Bibliografiska uppgifter
I publikationen:Rheumatology (Oxford)
Huvudupphovsmän: Nagai, Hideto, Kirino, Yohei, Nakano, Hiroto, Kunishita, Yosuke, Henmi, Riko, Szymanski, Ann Marie, Yoshimi, Ryusuke, Ombrello, Michael J, Nakajima, Hideaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Basic Science
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328498/
https://ncbi.nlm.nih.gov/pubmed/33550379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa814
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