GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease

BACKGROUND: Low C-C chemokine receptor 1 (CCR1) and interleukin (IL)-10 expression is associated with risk of Behçet’s disease (BD). The objective of the present study was to clarify the pathological roles of CCR1 and IL10 loci identified by previous BD genome-wide association studies (GWASs). METHO...

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Publicat a:Arthritis Res Ther
Autors principals: Nakano, Hiroto, Kirino, Yohei, Takeno, Mitsuhiro, Higashitani, Kana, Nagai, Hideto, Yoshimi, Ryusuke, Yamaguchi, Yukie, Kato, Ikuma, Aoki, Ichiro, Nakajima, Hideaki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998575/
https://ncbi.nlm.nih.gov/pubmed/29895319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1613-0
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