GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease

BACKGROUND: Low C-C chemokine receptor 1 (CCR1) and interleukin (IL)-10 expression is associated with risk of Behçet’s disease (BD). The objective of the present study was to clarify the pathological roles of CCR1 and IL10 loci identified by previous BD genome-wide association studies (GWASs). METHO...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Nakano, Hiroto, Kirino, Yohei, Takeno, Mitsuhiro, Higashitani, Kana, Nagai, Hideto, Yoshimi, Ryusuke, Yamaguchi, Yukie, Kato, Ikuma, Aoki, Ichiro, Nakajima, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998575/
https://ncbi.nlm.nih.gov/pubmed/29895319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1613-0
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