Relationship Between Amyloid-β Deposition and Blood–Brain Barrier Dysfunction in Alzheimer’s Disease

Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer’s disease (AD). The production and deposition of Aβ are important factors affecting AD progression and prognosis. The deposition of neurotoxic Aβ contributes to damage of the blood–brain barrier. However, the BBB is also crucial in ma...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Wang, Dong, Chen, Fanglian, Han, Zhaoli, Yin, Zhenyu, Ge, Xintong, Lei, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326917/
https://ncbi.nlm.nih.gov/pubmed/34349624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.695479
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