P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model

Accumulation of amyloid-β (Aβ) within extracellular spaces of the brain is a hallmark of Alzheimer disease (AD). In sporadic, late-onset AD, there is little evidence for increased Aβ production, suggesting that decreased elimination from the brain may contribute to elevated levels of Aβ and plaque f...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Cirrito, John R., Deane, Rashid, Fagan, Anne M., Spinner, Michael L., Parsadanian, Maia, Finn, Mary Beth, Jiang, Hong, Prior, Julie L., Sagare, Abhay, Bales, Kelly R., Paul, Steven M., Zlokovic, Berislav V., Piwnica-Worms, David, Holtzman, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2005
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257538/
https://ncbi.nlm.nih.gov/pubmed/16239972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25247
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller