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Low-density lipoprotein receptor-related protein-1 : a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brain

Low-density lipoprotein receptor-related protein-1 (LRP1), a member of the LDL receptor family, has major roles in the cellular transport of cholesterol, endocytosis of forty structurally diverse ligands, transcytosis of ligands across the blood-brain barrier, and transmembrane and nuclear signaling...

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Bibliografiske detaljer
Main Authors: Zlokovic, Berislav V., Deane, Rashid, Sagare, Abhay P., Bell, Robert D., Winkler, Ethan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972355/
https://ncbi.nlm.nih.gov/pubmed/20854368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07002.x
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